Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach.
نویسندگان
چکیده
The synthesis of 8-aminoquinolines and 1,10-phenanthrolines with substituents in α of the nitrogen has been performed through an inverse-demanding aza-Diels-Alder (Povarov reaction) in the fluoroalcohols TFE or HFIP. This path involves simple starting materials: 1,2-phenylenediamines, enol ethers and aldehydes.
منابع مشابه
A new practical approach towards the synthesis of unsymmetric and symmetric 1,10-phenanthroline derivatives at room temperature.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 2 شماره
صفحات -
تاریخ انتشار 2011